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Some other medications in Lunesta (Eszopiclone) pharmacological classes:
  • Alertec (Modafinil)
  • Ambien (Zolpidem)
  • Ativan (Lorazepam)
  • Quaalude (Methaqualone)
  • Circadin (Melatonin)
  • Dormison (Methylpentynol)
  • Clomethiazole (Chlormethiazole)
  • Imovane (Zopiclone)
  • Mechloral (Chloralodol)
  • Mogadon (Nitrazepam)
  • Nembutal (Pentobarbital)
  • Nopron (Niaprazine)
  • Precedex (Dexmedetomidine)
  • Presidon (Pyrithyldione)
  • Provigil (Modafinil)
  • Restoril (Temazepam)
  • Rohypnol (Flunitrazepam)
  • Rozerem (Ramelteon)
  • Sedormid (Apronal)
  • Sonata (Zaleplon)
  • Soneryl (Butobarbital)
  • Stilnox (Zolpidem)
  • Valium (Diazepam)
  • Versed (Midazolam)
  • Xanax (Alprazolam)

Lunesta (Eszopiclone)Eszopiclone (trade names include Lunesta; Eszop; Fulnite; Night Calm; Novo Insomnium; Valnoc) is a hypnotic and sedative medication from benzodiazepine related drugs pharmacological group. This medicine is used for the therapy of insomnia, especially where difficulty in falling asleep is the primary complaint. It causes relaxation to help you fall asleep and stay asleep. Eszopiclone works by affecting some chemicals in human brain that may become unbalanced and cause sleep problems (insomnia).

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General information about Eszopiclone (Lunesta):

Medical and pharmaceutical categories for eszopiclone:

  • Cyclopyrrolones
  • Hypnotic and sedative medicines
  • Anti-insomnia medications
  • Drugs for the treatment of sleep disorders
  • Nonbenzodiazepines
  • Sleeping pills
  • Z-drugs

The Anatomical Therapeutic Chemical (ATC) classification system eszopiclone codes:

  • N - Nervous system
  • N05 - Psycholeptics
  • N05C - Hypnotics and sedatives
  • N05CF - Benzodiazepine related drugs
  • N05CF04 - Eszopiclone

Eszopiclone in The International Statistical Classification of Diseases and Related Health Problems (World Health Organization, ICD-10) codes:

  • Nonorganic sleep disorders - F51
  • Sleep disorders - G47

Pregnancy categories for Eszopiclone (Lunesta):

  • Not classified - Australia
  • C - United States (Risk cannot be ruled out)

Salts and other eszopiclone forms used as active pharmaceutical ingredients (API):

  • Eszopiclone Base

Derivatives and other similar forms of eszopiclone used as active pharmaceutical ingredients (API):

  • Zopiclone

Synonyms of eszopiclone, international and chemical names:

  • (+)-Zopiclone
  • (S)-Zopiclone
  • Dextrorotatory stereoisomer of Zopiclone
  • Esopiclone
  • Eszopiclon
  • Eszopiclona
  • Eszopicloni
  • Eszopiclonum
  • Eszopiklon

Best known eszopiclone brands, generics and trade names in various countries:

  • Estorra - Sepracor Pharmaceuticals
  • Eszop - Silesia Laboratorios
  • Eszopiclone - Dr. Reddy's Laboratories; Lupin Pharmaceuticals; Mylan; Roxane Laboratories; Sun Pharmaceutical Industries; Teva
  • Fulnite - Sun Pharmaceutical Industries
  • JustSleep - Emcure Pharmaceuticals
  • Lunesta - Sepracor Pharmaceuticals
  • Night Calm - Medizen Pharmaceutical Industries
  • Nirvan - Saval Laboratorios
  • Novo Insomnium - Gador
  • Plessir - Medipharm
  • Sleepez - ChemiPharm
  • Valnoc - Drugtech Laboratorio
  • Zopimin

Here is a list of some medications containing "Eszopiclone" as a main active pharmaceutical ingredient (API) of eszopiclone drugs, their trade names, available forms, doses and also pharmaceutical companies - manufacturers, distributors and suppliers, researchers and developers:

Trade name of the drug Pharmaceutical forms and doses Companies
  • Tablets; Oral; Eszopiclone 1 mg
  • Tablets; Oral; Eszopiclone 2 mg
  • Sun Pharmaceutical Industries
  • Tablets; Oral; Eszopiclone 2 mg
  • Emcure Pharmaceuticals
  • Tablets; Oral; Eszopiclone 1 mg
  • Tablets; Oral; Eszopiclone 2 mg
  • Tablets; Oral; Eszopiclone 3 mg
  • Sepracor Pharmaceuticals
  • Eisai
  • Sunovion Pharmaceuticals
  • Tablets; Oral; Eszopiclone 2 mg
  • Tablets; Oral; Eszopiclone 3 mg
  • Sepracor Pharmaceuticals
Novo Insomnium
  • Tablets, Film-Coated; Oral; Eszopiclone 2 mg
  • Tablets, Film-Coated; Oral; Eszopiclone 3 mg
  • Gador
  • Tablets, Film-Coated; Oral; Eszopiclone 1 mg
  • Tablets, Film-Coated; Oral; Eszopiclone 2 mg
  • Tablets, Film-Coated; Oral; Eszopiclone 3 mg
  • ChemiPharm
  • Tablets, Film-Coated; Oral; Eszopiclone 2 mg
  • Tablets, Film-Coated; Oral; Eszopiclone 3 mg
  • Drugtech Laboratorio
  • Farmindustria
  • Recalcine Laboratorios
  • Synthesis Laboratorios
  • Tablets; Oral; Eszopiclone 1 mg
  • Tablets; Oral; Eszopiclone 2 mg
  • Psyco Remedies

How to take

Dosage In Adults:

The recommended starting dose is 1 mg. Dosing can be raised to 2 mg or 3 mg if clinically indicated. In some patients, the higher morning blood levels of LUNESTA following use of the 2 mg or 3 mg dose increase the risk of next day impairment of driving and other activities that require full alertness. The total dose of LUNESTA should not exceed 3 mg, once daily immediately before bedtime.

Geriatric Or Debilitated Patients:

The total dose of LUNESTA should not exceed 2 mg in elderly or debilitated patients.

Patients With Severe Hepatic Impairment:

In patients with severe hepatic impairment the total dose of LUNESTA should not exceed 2 mg.

Use With CNS Depressants:

Dosage adjustments may be necessary when LUNESTA is combined with other CNS depressant drugs because of the potentially additive effects.

Administration With Food:

Taking LUNESTA with or immediately after a heavy, high-fat meal results in slower absorption and would be expected to reduce the effect of LUNESTA on sleep latency

Side effects

Eszopiclone may cause a severe allergic reaction. Stop taking eszopiclone and get emergency medical help if you have any of thesesigns of an allergic reaction:

  • hives;
  • difficulty breathing;
  • swelling of your face, lips, tongue, or throat.

Stop using eszopiclone and call your doctor at once if you have any of these serious side effects:

  • aggression, agitation, changes in behavior;
  • thoughts of hurting yourself; or
  • hallucinations (hearing or seeing things).

Less serious side effects may include:

  • day-time drowsiness, dizziness, "hangover" feeling;
  • problems with memory or concentration;
  • anxiety, depression, nervous feeling;
  • headache;
  • nausea, stomach pain, loss of appetite, constipation;
  • dry mouth;
  • unusual or unpleasant taste in your mouth; or
  • mild skin rash.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.


Eszopiclone will make you fall asleep. Never take this medication during your normal waking hours, unless you have at least 8 hours to dedicate to sleeping.

Some people using this medicine have engaged in activity such as driving, eating, or making phone calls and later having no memory of the activity.

If this happens to you, stop taking eszopiclone and talk with your doctor about another treatment for your sleep disorder.

Eszopiclone can cause side effects that may impair your thinking or reactions. You may still feel sleepy the morning after taking the medication. Until you know how this medication will affect you during waking hours, be careful if you drive, operate machinery, pilot an airplane, or do anything that requires you to be awake and alert.

Do not drink alcohol while you are taking eszopiclone. It can increase some of the side effects of eszopiclone, including drowsiness.

Eszopiclone may be habit-forming andshould be used only by the person it was prescribed for. Eszopiclone should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

You may have withdrawal symptoms if you stop taking eszopiclone after taking it over several days in a row.

Do not stop taking eszopiclone suddenlywithout first talking to your doctor. You may need to use less and less before you stop the medication completely.

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